Across TCGA patient cohorts, ZFP2 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP2-associated genes across cancer lineages are INPP4B, MEK1, and p38-MAPK_pT180_Y182. Each is linked with ZFP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP2-to-partner and partner-to-ZFP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP2→partner) and Y-score (partner→ZFP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.308	-2.070	.001	.001	3	2
UCEC	MEK1 →	+0.405	+1.947	<.001	<.001	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.310	-1.249	.024	.019	3	2
UCEC	PDCD4 →	-0.448	-1.263	.001	.019	3	2
UCEC	Shc_pY317 →	-0.179	-1.925	<.001	.004	3	2
UCEC	ASNS →	+0.271	+1.247	.014	.041	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

ZFP2 survival (RNA) · tumor vs normal (RNA) · all ZFP2 data types