ZFP14

Across TCGA patient cohorts, ZFP14 mutation is significantly associated with the RNA expression of many other genes, with 1,840 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP14-associated genes across cancer lineages are AATF, CCL27, and ESS2. Each is linked with ZFP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP14-to-partner and partner-to-ZFP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AATF grouped by ZFP14-low versus ZFP14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP14→partner) and Y-score (partner→ZFP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AATF →	+0.384	+2.263	.001	<.001	3	2
CESC	CCL27 →	+0.065	+4.812	<.001	.006	3	2
UCEC	ESS2 →	+0.279	+3.906	.001	<.001	3	2
UCEC	MCM5 →	+0.587	+1.949	<.001	.001	3	2
UCEC	ASCC2 →	+0.270	+2.013	.001	<.001	3	2
UCEC	UQCRC1 →	+0.375	+3.016	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,840 associations by consensus.

AATF by ZFP14 expression — UCEC

Explore this box plot interactively →