ZFP14

Across TCGA cell cohorts, ZFP14 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,471 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZFP14-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, and mRNA splicing, via spliceosome. Each is linked with ZFP14 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZFP14-to-partner and partner-to-ZFP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA splicing, via transesterification reactions grouped by ZFP14-low versus ZFP14-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP14→partner) and Y-score (partner→ZFP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	RNA splicing, via transesterification reactions →	+0.064	+0.674	.003	.003	3	15
LUNG_SCLC	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.065	+0.834	.003	.001	3	15
LUNG_SCLC	mRNA splicing, via spliceosome →	+0.065	+0.834	.003	.001	3	15
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.093	+0.887	<.001	<.001	3	14
BONE	Positive regulation of DNA repair →	+0.081	+0.996	<.001	<.001	3	14
BONE	Intraciliary transport →	+0.091	+1.092	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,471 associations by consensus.

RNA splicing, via transesterification reactions by ZFP14 expression — LUNG_SCLC

Explore this box plot interactively →