ZFP14

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZFP14 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFP14-associated genes across cancer lineages are ACSM6, CFHR2, and FABP12. Each is linked with ZFP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP14-to-partner and partner-to-ZFP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACSM6 grouped by ZFP14-low versus ZFP14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP14→partner) and Y-score (partner→ZFP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEACSM6 →+0.023+3.658<.001.00531
LARGE_INTESTINECFHR2 →+0.038+4.022<.001.00631
BLOOD_LeukemiaFABP12 →+0.085+5.201<.001.00631
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ACSM6 by ZFP14 expression — LARGE_INTESTINE

Box plot of ACSM6 in ZFP14-low vs ZFP14-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration