Across TCGA pan-cancer cohorts, ZFP1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZFP1 data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ZFP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZFP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

STAD, UCEC, and CESC are the cancer types where ZFP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	II,III,IV	0.183	0.676	.007	12	view →
UCEC	DFS	Median	III,IV	1.000	0.535	.030	8	view →
CESC	DFS	Median	All	0.088	0.545	.004	6	view →
SCLC	DFS	Median	II,III,IV	0.164	0.602	.021	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: ZFP1 tumor-vs-normal RNA expression · all ZFP1 data types