ZFP1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZFP1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZFP1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZFP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZFP1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

UCEC and GBM are the cancer types where ZFP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianAll0.8160.977.02110view →
GBMOSTertileAll0.7680.224.0017view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration