Across TCGA cell cohorts, ZFP1 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZFP1-associated genes across cancer lineages are UTF1, LGI1, and GFRA4. Each is linked with ZFP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP1-to-partner and partner-to-ZFP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP1→partner) and Y-score (partner→ZFP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UTF1 →	+0.015	+3.632	<.001	.003	3	1
BLOOD_Leukemia	LGI1 →	+0.096	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GFRA4 →	+0.295	+4.409	.001	.005	3	1
BLOOD_Leukemia	KERA →	+0.006	+4.551	.002	.004	3	1
BLOOD_Leukemia	RGR →	+0.045	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	GPR26 →	+0.057	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

ZFP1 survival (RNA) · tumor vs normal (RNA) · all ZFP1 data types