ZFHX4-AS1

Across TCGA pan-cancer cohorts, ZFHX4-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ZFHX4-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZFHX4-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZFHX4-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

KIRC, BLCA, and OV are the cancer types where ZFHX4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.543	0.682	<.001	100	view →
BLCA	OS	Median	All	0.533	0.685	<.001	90	view →
OV	DFS	Tertile	All	0.482	0.619	<.001	88	view →
KICH	OS	Tertile	III,IV	0.159	0.847	<.001	87	view →
UCS	OS	Median	III,IV	0.736	0.413	.005	70	view →
UCEC	OS	Tertile	All	0.548	0.725	<.001	68	view →
STAD	OS	Tertile	All	0.510	0.678	.001	61	view →
ACC	DFS	Median	All	0.236	0.633	<.001	50	view →
SKCM	OS	Median	IV	0.836	0.348	<.001	29	view →
LUAD	DFS	Tertile	II,III,IV	0.361	0.597	.004	28	view →
CHOL	DFS	Tertile	II,III,IV	0.792	0.118	.010	23	view →
SARC	OS	Median	All	0.626	0.825	.003	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ZFHX4-AS1–KIRC (DFS)

Open the KIRC breakdown →