ZFHX3

Across TCGA cell cohorts, ZFHX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,587 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZFHX3-associated GO terms across cancer lineages are Viral transcription, Positive regulation of organelle assembly, and Late viral transcription. Each is linked with ZFHX3 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZFHX3-to-partner and partner-to-ZFHX3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral transcription grouped by ZFHX3-low versus ZFHX3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFHX3→partner) and Y-score (partner→ZFHX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Viral transcription →	+0.134	+0.926	.001	<.001	2	17
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.059	+0.959	.001	<.001	3	15
LUNG_SCLC	Late viral transcription →	+0.139	+0.883	.001	.001	3	15
BONE	Cytosolic transport →	+0.091	+0.961	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of gene expression, epigenetic →	+0.047	+0.674	<.001	<.001	3	14
OESOPHAGUS	CAMP/PKA signal transduction →	+0.220	+0.885	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,587 associations by consensus.

Viral transcription by ZFHX3 expression — LUNG_SCLC

Explore this box plot interactively →