ZFHX2

Across TCGA patient cohorts, ZFHX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,350 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZFHX2-associated proteins across cancer lineages are MYEF2, P4HB, and EIF3H_S183. Each is linked with ZFHX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZFHX2-to-partner and partner-to-ZFHX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFHX2 versus MYEF2 in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFHX2→partner) and Y-score (partner→ZFHX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MYEF2 →	+1.059	+0.451	<.001	<.001	3	4
GBM	P4HB →	-0.492	-0.721	<.001	<.001	3	4
BRCA	EIF3H_S183 →	-0.433	-0.324	<.001	<.001	3	4
LSCC	PRR36 →	+1.360	+0.389	<.001	.001	3	4
LSCC	PRR36_S229 →	+1.787	+0.479	<.001	<.001	3	4
BRCA	RPS13 →	-0.302	-0.418	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,350 associations by consensus.

ZFHX2 vs MYEF2 — LSCC

Explore this scatter interactively →