ZFAT

Across TCGA patient cohorts, ZFAT protein abundance is significantly associated with the RNA expression of many other genes, with 2,058 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZFAT-associated genes across cancer lineages are RNU6-25P, RASL10A, and LRRC74A. Each is linked with ZFAT in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFAT-to-partner and partner-to-ZFAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFAT versus RNU6-25P in OV, with a Pearson correlation of -0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAT→partner) and Y-score (partner→ZFAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RNU6-25P →	-2.005	-1.451	.008	.003	3	2
CCRCC	RASL10A →	-0.722	-0.491	.003	.006	3	1
CCRCC	LRRC74A →	-0.697	-0.557	.002	.004	3	1
CCRCC	PDGFRL →	-2.135	-0.511	.003	.007	3	1
CCRCC	FAM20A →	-1.342	-0.465	.007	.002	2	2
CCRCC	ADAM23 →	-0.787	-0.554	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,058 associations by consensus.

ZFAT vs RNU6-25P — OV

Explore this scatter interactively →