ZFAND6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZFAND6 mutation is significantly associated with the RNA expression of many other genes, with 204 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFAND6-associated genes across cancer lineages are RNA5SP319, MRM1, and MIR98. Each is linked with ZFAND6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFAND6-to-partner and partner-to-ZFAND6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP319 grouped by ZFAND6-low versus ZFAND6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND6→partner) and Y-score (partner→ZFAND6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNA5SP319 →+0.328+5.097<.001.00832
UCECMRM1 →+0.568+3.343.007.00531
UCECMIR98 →+0.298+2.994.002.00331
UCECSTMN1P1 →+0.466+3.523.002.00431
HNSCRNU6-492P →+0.478+7.954<.001.00831
HNSCRNU4-26P →+0.268+7.954<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 204 associations by consensus.

RNA5SP319 by ZFAND6 expression — SKCM

Box plot of RNA5SP319 in ZFAND6-low vs ZFAND6-high samples in SKCM.

Explore this box plot interactively →

Exploration