ZFAND5

Across TCGA patient cohorts, ZFAND5 mutation is significantly associated with the RNA expression of many other genes, with 2,062 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFAND5-associated genes across cancer lineages are RNU6-704P, RNU6-1305P, and RNU6-487P. Each is linked with ZFAND5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFAND5-to-partner and partner-to-ZFAND5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-704P grouped by ZFAND5-low versus ZFAND5-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND5→partner) and Y-score (partner→ZFAND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-704P →	+0.585	+3.626	<.001	.001	3	1
CESC	RNU6-1305P →	+0.276	+3.507	<.001	.005	3	1
CESC	RNU6-487P →	+0.293	+4.397	<.001	<.001	3	1
CESC	MIR548N →	+0.493	+3.194	<.001	.005	3	1
CESC	H3P26 →	+0.176	+3.239	<.001	.005	3	1
CESC	RPS18P1 →	+0.184	+3.934	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,062 associations by consensus.

RNU6-704P by ZFAND5 expression — CESC

Explore this box plot interactively →