ZFAND5

Across TCGA patient cohorts, ZFAND5 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFAND5-associated genes across cancer lineages are ASNS, 14-3-3_beta, and INPP4B. Each is linked with ZFAND5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFAND5-to-partner and partner-to-ZFAND5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZFAND5-low versus ZFAND5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND5→partner) and Y-score (partner→ZFAND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.541	+2.115	<.001	.017	3	2
UCEC	14-3-3_beta →	-0.091	-3.143	.018	.018	3	1
UCEC	INPP4B →	-0.321	-3.807	.009	<.001	3	1
UCEC	JNK2 →	+0.308	+2.584	<.001	.001	3	1
UCEC	Ku80 →	+0.191	+1.691	.035	.014	3	1
UCEC	MEK1 →	+0.300	+2.222	.032	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

ASNS by ZFAND5 expression — UCEC

Explore this box plot interactively →