ZFAND4

Across TCGA cell cohorts, ZFAND4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,131 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZFAND4-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Nucleotide-excision repair, and Regulation of microtubule depolymerization. Each is linked with ZFAND4 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZFAND4-to-partner and partner-to-ZFAND4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by ZFAND4-low versus ZFAND4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND4→partner) and Y-score (partner→ZFAND4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.170	+1.186	.001	.002	3	13
LIVER	Nucleotide-excision repair →	+0.070	+0.783	.007	.004	3	11
OVARY	Regulation of microtubule depolymerization →	+0.092	+0.718	.006	<.001	3	10
LUNG_NSCLC_LUSC	DNA synthesis involved in DNA repair →	+0.124	+1.062	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	DNA biosynthetic process →	+0.083	+0.789	<.001	<.001	3	10
STOMACH	Protein localization to non-motile cilium →	+0.072	+0.900	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,131 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by ZFAND4 expression — OESOPHAGUS

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