ZFAND2A

Across TCGA pan-cancer cohorts, ZFAND2A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZFAND2A data layer compared with 24 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ZFAND2A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZFAND2A expression acts as an unfavorable survival marker.

COAD and CHOL are the cancer types where ZFAND2A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	II,III,IV	0.054	0.860	<.001	24	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZFAND2A–COAD (OS)

Open the COAD breakdown →