ZFAND2A

Across TCGA patient cohorts, ZFAND2A mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ZFAND2A-associated genes across cancer lineages are RNA5SP327, AP1B1P1, and RNU7-54P. Each is linked with ZFAND2A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFAND2A-to-partner and partner-to-ZFAND2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP327 grouped by ZFAND2A-low versus ZFAND2A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND2A→partner) and Y-score (partner→ZFAND2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP327 →	+0.308	+7.741	<.001	.009	3	1
SKCM	AP1B1P1 →	+0.088	+4.296	.007	.008	3	1
SKCM	RNU7-54P →	+0.433	+4.771	<.001	.006	3	1
SKCM	RNU7-194P →	+0.439	+5.080	<.001	.004	3	1
SKCM	NDUFA5P5 →	+0.101	+4.594	<.001	.008	3	1
UCEC	MIR4470 →	+0.509	+3.186	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

RNA5SP327 by ZFAND2A expression — COAD

Explore this box plot interactively →