ZFAND2A

Across TCGA cell cohorts, ZFAND2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,545 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZFAND2A-associated GO terms across cancer lineages are Establishment of protein localization to endoplasmic reticulum, Protein targeting to ER, and Post-translational protein targeting to endoplasmic reticulum membrane. Each is linked with ZFAND2A in more than 15 cancer types. Because this analysis shows association rather than direction, both ZFAND2A-to-partner and partner-to-ZFAND2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to endoplasmic reticulum grouped by ZFAND2A-low versus ZFAND2A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND2A→partner) and Y-score (partner→ZFAND2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Establishment of protein localization to endoplasmic reticulum →	+0.091	+0.885	.007	.005	3	16
BONE	Protein targeting to ER →	+0.126	+0.801	<.001	.008	3	14
BLOOD_Lymphoma	Post-translational protein targeting to endoplasmic reticulum membrane →	+0.115	+1.086	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Maintenance of unfolded protein →	+0.143	+0.800	<.001	.002	2	12
UPPER_AERODIGESTIVE_TRACT	Meiotic attachment of telomere to nuclear envelope →	+0.134	+0.834	.002	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to membrane →	+0.042	+0.669	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,545 associations by consensus.

Establishment of protein localization to endoplasmic reticulum by ZFAND2A expression — STOMACH

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