ZFAND1

Across TCGA patient cohorts, ZFAND1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFAND1-associated genes across cancer lineages are Endothelial cells, Mesangial cells, and mv Endothelial cells. Each is linked with ZFAND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFAND1-to-partner and partner-to-ZFAND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by ZFAND1-low versus ZFAND1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND1→partner) and Y-score (partner→ZFAND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.048	-3.542	.008	.003	3	1
UCEC	Mesangial cells →	-0.054	-3.305	.003	.010	3	1
UCEC	mv Endothelial cells →	-0.029	-2.448	.009	.020	3	1
UCEC	pDC →	+0.073	+2.839	.001	.034	3	1
UCEC	Class-switched memory B-cells →	-0.059	-2.459	.032	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Endothelial cells by ZFAND1 expression — UCEC

Explore this box plot interactively →