ZFAND1

Across TCGA cell cohorts, ZFAND1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,063 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZFAND1-associated GO terms across cancer lineages are Response to arsenite ion, Cellular response to arsenite ion, and Negative regulation of hematopoietic stem cell differentiation. Each is linked with ZFAND1 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZFAND1-to-partner and partner-to-ZFAND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to arsenite ion grouped by ZFAND1-low versus ZFAND1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND1→partner) and Y-score (partner→ZFAND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to arsenite ion →	+0.159	+1.219	<.001	<.001	3	15
BONE	Cellular response to arsenite ion →	+0.159	+1.219	<.001	<.001	3	15
LUNG_SCLC	Negative regulation of hematopoietic stem cell differentiation →	+0.155	+0.725	<.001	<.001	3	10
BREAST	Mitotic cytokinesis checkpoint signaling →	+0.146	+1.031	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Cellular response to arsenic-containing substance →	+0.078	+1.028	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein polyufmylation →	+0.080	+0.722	.003	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,063 associations by consensus.

Response to arsenite ion by ZFAND1 expression — BONE

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