ZDHHC8P1

Across TCGA pan-cancer cohorts, ZDHHC8P1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZDHHC8P1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ZDHHC8P1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZDHHC8P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

PDAC, HNSC, and LUAD are the cancer types where ZDHHC8P1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.475	0.991	.013	16	view →
HNSC	DFS	Quartile	II,III,IV	0.844	0.366	.002	15	view →
LUAD	DFS	Median	II,III,IV	0.338	0.964	.038	3	view →
LSCC	DFS	Median	All	0.456	1.000	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZDHHC8P1–PDAC (DFS)

Open the PDAC breakdown →