ZDHHC8P1

Across TCGA patient cohorts, ZDHHC8P1 mutation is significantly associated with the RNA expression of many other genes, with 290 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC8P1-associated genes across cancer lineages are YBX1P9, PACSIN2, and CACTIN. Each is linked with ZDHHC8P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC8P1-to-partner and partner-to-ZDHHC8P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, YBX1P9 grouped by ZDHHC8P1-low versus ZDHHC8P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC8P1→partner) and Y-score (partner→ZDHHC8P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	YBX1P9 →	+0.118	+2.538	.002	.001	3	2
UCEC	PACSIN2 →	+0.579	+3.191	.001	.009	3	1
UCEC	CACTIN →	+0.415	+3.212	.003	.009	3	1
UCEC	PIGL →	+0.419	+2.638	.003	.005	3	1
UCEC	MRPS15 →	+0.505	+3.212	.002	.009	3	1
UCEC	CTNNAL1 →	+0.775	+3.213	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 290 associations by consensus.

YBX1P9 by ZDHHC8P1 expression — UCEC

Explore this box plot interactively →