ZDHHC8

Across TCGA patient cohorts, ZDHHC8 protein abundance is significantly associated with the RNA expression of many other genes, with 2,541 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZDHHC8-associated genes across cancer lineages are LINC00667, NDUFS6P1, and LRRC74A. Each is linked with ZDHHC8 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC8-to-partner and partner-to-ZDHHC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC8 versus LINC00667 in HNSC, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC8→partner) and Y-score (partner→ZDHHC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC00667 →	-1.175	-0.406	<.001	<.001	3	2
PDAC	NDUFS6P1 →	-0.666	-1.104	.004	.007	3	1
UCEC	LRRC74A →	+0.544	+0.459	.001	<.001	3	1
UCEC	PTPN5 →	+0.196	+0.573	.007	.008	3	1
UCEC	AMPD1 →	+0.576	+0.459	<.001	<.001	3	1
UCEC	CCDC62 →	+0.335	+0.459	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,541 associations by consensus.

ZDHHC8 vs LINC00667 — HNSC

Explore this scatter interactively →