ZDHHC7

Across TCGA pan-cancer cohorts, ZDHHC7 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ZDHHC7’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ZDHHC7 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types ZDHHC7 is over-expressed in tumor.

LUAD, PDAC, and LSCC are the cancer types where ZDHHC7 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZDHHC7 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+0.999	<.001	9	view →
PDAC	Female	II,III,IV	+1.030	<.001	7	view →
LSCC	Male	All	+0.365	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ZDHHC7–LUAD

Open the LUAD breakdown →