ZDHHC5

Across TCGA cell cohorts, ZDHHC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,758 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZDHHC5-associated GO terms across cancer lineages are Regulation of nucleocytoplasmic transport, Vacuole organization, and Vacuolar transport. Each is linked with ZDHHC5 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZDHHC5-to-partner and partner-to-ZDHHC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleocytoplasmic transport grouped by ZDHHC5-low versus ZDHHC5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC5→partner) and Y-score (partner→ZDHHC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of nucleocytoplasmic transport →	+0.068	+0.602	<.001	.004	3	14
BLOOD_Myeloma	Vacuole organization →	+0.061	+0.796	<.001	<.001	3	13
OVARY	Vacuolar transport →	+0.068	+0.707	<.001	<.001	3	13
LARGE_INTESTINE	Endosomal transport →	+0.051	+0.701	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.059	+0.757	.001	<.001	3	12
BLOOD_Lymphoma	Regulation of intracellular transport →	+0.041	+0.516	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,758 associations by consensus.

Regulation of nucleocytoplasmic transport by ZDHHC5 expression — BONE

Explore this box plot interactively →