ZDHHC4

Across TCGA patient cohorts, ZDHHC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,432 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZDHHC4-associated proteins across cancer lineages are NUDCD3, WDFY4, and PTPRC. Each is linked with ZDHHC4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZDHHC4-to-partner and partner-to-ZDHHC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC4 versus NUDCD3 in GBM, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC4→partner) and Y-score (partner→ZDHHC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NUDCD3 →	+0.401	+0.566	<.001	<.001	3	8
OV	WDFY4 →	-0.440	-0.449	.002	.003	3	6
GBM	PTPRC →	-0.748	-0.379	<.001	<.001	3	5
LSCC	SUN1 →	+0.291	+0.377	<.001	.001	3	5
LSCC	ZNF316_S112 →	+0.410	+0.468	<.001	<.001	3	5
COAD	EIF4H →	+0.263	+0.330	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,432 associations by consensus.

ZDHHC4 vs NUDCD3 — GBM

Explore this scatter interactively →