ZDHHC4

Across TCGA patient cohorts, ZDHHC4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,878 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZDHHC4-associated genes across cancer lineages are CD53, CD84, and TXK. Each is linked with ZDHHC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZDHHC4-to-partner and partner-to-ZDHHC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC4 versus CD53 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC4→partner) and Y-score (partner→ZDHHC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD53 →	-0.768	-0.459	<.001	<.001	3	3
GBM	CD84 →	-0.656	-0.433	<.001	<.001	3	3
LSCC	TXK →	-0.699	-0.377	<.001	<.001	3	3
GBM	PTPRC →	-0.749	-0.375	<.001	.001	3	3
LSCC	PIK3IP1 →	-0.575	-0.417	<.001	<.001	3	3
GBM	C17orf75 →	+0.454	+0.546	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,878 associations by consensus.

ZDHHC4 vs CD53 — GBM

Explore this scatter interactively →