Across TCGA patient cohorts, ZDHHC23 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC23-associated genes across cancer lineages are ASNS, Caspase-7-cleavedD198, and C-Raf. Each is linked with ZDHHC23 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC23-to-partner and partner-to-ZDHHC23 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC23→partner) and Y-score (partner→ZDHHC23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.298	+2.807	.017	.003	3	2
UCEC	Caspase-7-cleavedD198 →	+0.512	+2.242	.012	.005	3	2
UCEC	C-Raf →	+0.121	+1.807	.015	.025	3	2
UCEC	14-3-3_beta →	-0.113	-2.780	.001	.003	3	1
UCEC	eEF2 →	+0.305	+2.459	.013	.018	3	1
UCEC	EGFR_pY1068 →	-0.287	-1.906	<.001	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

ZDHHC23 survival (RNA) · tumor vs normal (RNA) · all ZDHHC23 data types