ZDHHC20

Across TCGA patient cohorts, ZDHHC20 protein abundance is significantly associated with the RNA expression of many other genes, with 6,189 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZDHHC20-associated genes across cancer lineages are CXCL10, CXCL11, and CARD8. Each is linked with ZDHHC20 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZDHHC20-to-partner and partner-to-ZDHHC20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC20 versus CXCL10 in HNSC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC20→partner) and Y-score (partner→ZDHHC20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CXCL10 →	-2.062	-0.251	<.001	<.001	3	3
COAD	CXCL11 →	-1.958	-0.257	<.001	.003	3	3
HNSC	CARD8 →	-0.450	-0.208	<.001	.003	3	3
HNSC	CD22 →	-0.693	-0.214	<.001	.003	3	3
GBM	ZNF835 →	-0.508	-0.317	<.001	<.001	3	3
HNSC	HERC5 →	-1.079	-0.333	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,189 associations by consensus.

ZDHHC20 vs CXCL10 — HNSC

Explore this scatter interactively →