ZDHHC20

Across TCGA cell cohorts, ZDHHC20 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,883 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZDHHC20-associated GO terms across cancer lineages are Regulation of sister chromatid segregation, Positive regulation of cytoplasmic mRNA processing body assembly, and Positive regulation of chromosome segregation. Each is linked with ZDHHC20 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZDHHC20-to-partner and partner-to-ZDHHC20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of sister chromatid segregation grouped by ZDHHC20-low versus ZDHHC20-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC20→partner) and Y-score (partner→ZDHHC20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of sister chromatid segregation →	+0.090	+0.931	<.001	<.001	3	13
BLOOD_Lymphoma	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.132	+0.975	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of chromosome segregation →	+0.141	+0.736	.003	.001	3	12
SOFT_TISSUE	Regulation of mitotic sister chromatid separation →	+0.103	+0.879	.008	<.001	3	12
OESOPHAGUS	Regulation of metaphase/anaphase transition of cell cycle →	+0.105	+0.927	.002	.006	2	13
OESOPHAGUS	Regulation of chromosome segregation →	+0.096	+0.950	.005	.005	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,883 associations by consensus.

Regulation of sister chromatid segregation by ZDHHC20 expression — BLOOD_Lymphoma

Explore this box plot interactively →