ZDHHC2

Across TCGA patient cohorts, ZDHHC2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,995 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZDHHC2-associated genes across cancer lineages are ITGB8, NR2C2AP, and RNU6-529P. Each is linked with ZDHHC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZDHHC2-to-partner and partner-to-ZDHHC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC2 versus ITGB8 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC2→partner) and Y-score (partner→ZDHHC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ITGB8 →	+2.191	+0.577	.008	.008	2	3
OV	NR2C2AP →	-1.100	-0.623	.004	.006	2	3
OV	RNU6-529P →	+1.540	+0.700	<.001	<.001	3	2
OV	HS1BP3-IT1 →	+0.874	+0.629	<.001	.006	3	2
LUAD	HMGB1P21 →	-0.806	-0.477	<.001	<.001	3	2
OV	LINC01842 →	-1.892	-0.594	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,995 associations by consensus.

ZDHHC2 vs ITGB8 — OV

Explore this scatter interactively →