ZDHHC2

Across TCGA cell cohorts, ZDHHC2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,953 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZDHHC2-associated genes across cancer lineages are YAP1, EED, and POLD3. Each is linked with ZDHHC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZDHHC2-to-partner and partner-to-ZDHHC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC2 versus YAP1 in STOMACH, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC2→partner) and Y-score (partner→ZDHHC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	YAP1 →	+1.601	+1.673	.007	<.001	3	9
OESOPHAGUS	EED →	+0.980	+0.876	.001	.001	3	5
LUNG_NSCLC_LUAD	POLD3 →	+0.700	+1.084	.003	.002	3	5
LARGE_INTESTINE	SGO1 →	+0.826	+1.069	.001	.001	3	5
STOMACH	SUPT20H →	+1.036	+1.533	<.001	.002	3	4
PANCREAS	KIFC1 →	+1.311	+1.097	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,953 associations by consensus.

ZDHHC2 vs YAP1 — STOMACH

Explore this scatter interactively →