ZDHHC19

Across TCGA patient cohorts, ZDHHC19 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,144 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZDHHC19-associated GO terms across cancer lineages are Negative regulation of production of molecular mediator of immune response, T cell proliferation, and Detoxification. Each is linked with ZDHHC19 in more than 19 cancer types. Because this analysis shows association rather than direction, both ZDHHC19-to-partner and partner-to-ZDHHC19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of production of molecular mediator of immune response grouped by ZDHHC19-low versus ZDHHC19-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC19→partner) and Y-score (partner→ZDHHC19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of production of molecular mediator of immune response →	+0.054	+0.276	<.001	<.001	3	20
STAD	T cell proliferation →	+0.058	+0.134	<.001	<.001	3	19
ESCA	Detoxification →	+0.047	+0.379	<.001	<.001	3	19
ESCA	Multi-pass transmembrane protein insertion into ER membrane →	+0.073	+0.319	<.001	.001	3	19
ESCA	Regulation of response to cytokine stimulus →	+0.046	+0.334	.001	<.001	3	18
STAD	Positive regulation of macrophage migration →	+0.069	+0.169	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,144 associations by consensus.

Negative regulation of production of molecular mediator of immune response by ZDHHC19 expression — ESCA

Explore this box plot interactively →