Across TCGA patient cohorts, ZDHHC18 protein abundance is significantly associated with the RNA expression of many other genes, with 3,761 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZDHHC18-associated genes across cancer lineages are GPALPP1, FANCM, and CHRDL1. Each is linked with ZDHHC18 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZDHHC18-to-partner and partner-to-ZDHHC18 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC18→partner) and Y-score (partner→ZDHHC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GPALPP1 →	-0.509	-0.651	.001	.002	3	3
HNSC	FANCM →	-0.517	-0.762	.001	.001	3	3
UCEC	CHRDL1 →	-1.795	-0.525	<.001	.001	3	3
CCRCC	RECK →	-0.973	-0.776	<.001	.002	3	3
CCRCC	DIPK2B →	-1.800	-0.882	.003	.008	3	3
CCRCC	GSN →	-1.340	-1.204	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,761 associations by consensus.

Exploration

ZDHHC18 survival (RNA) · tumor vs normal (RNA) · all ZDHHC18 data types