Across TCGA patient cohorts, ZDHHC18 mutation is significantly associated with the RNA expression of many other genes, with 1,203 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC18-associated genes across cancer lineages are BUD13P1, GPR75-ASB3, and IGHV3OR16-13. Each is linked with ZDHHC18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC18-to-partner and partner-to-ZDHHC18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC18→partner) and Y-score (partner→ZDHHC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BUD13P1 →	+0.143	+2.030	.001	.002	3	1
UCEC	GPR75-ASB3 →	+0.054	+1.674	.005	.009	3	1
UCEC	IGHV3OR16-13 →	+0.589	+1.841	<.001	.002	3	1
UCEC	POM121C →	+0.400	+2.724	.001	.003	3	1
UCEC	TAF9 →	+0.493	+2.247	<.001	.002	3	1
UCEC	NOL12 →	+0.278	+3.202	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,203 associations by consensus.

Exploration

ZDHHC18 survival (RNA) · tumor vs normal (RNA) · all ZDHHC18 data types