ZDHHC18

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZDHHC18 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,346 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZDHHC18-associated GO terms across cancer lineages are Regulation of pattern recognition receptor signaling pathway, Negative regulation of cytoplasmic pattern recognition receptor signaling pathway, and Negative regulation of DNA-templated transcription initiation. Each is linked with ZDHHC18 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZDHHC18-to-partner and partner-to-ZDHHC18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC18→partner) and Y-score (partner→ZDHHC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRegulation of pattern recognition receptor signaling pathway →+0.055+1.046.004<.001216
LARGE_INTESTINENegative regulation of cytoplasmic pattern recognition receptor signaling pathway →+0.078+0.945<.001<.001315
STOMACHNegative regulation of DNA-templated transcription initiation →+0.140+0.962<.001.004313
STOMACHNegative regulation of transcription initiation by RNA polymerase II →+0.140+0.962<.001.004313
BREASTRegulation of protein localization to nucleus →+0.090+0.820<.001<.001312
STOMACHPre-miRNA processing →+0.112+1.320.002.002312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,346 associations by consensus.

Exploration