Across TCGA cell cohorts, ZDHHC18 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZDHHC18-associated genes across cancer lineages are GJD2, SLC15A5, and EPPIN. Each is linked with ZDHHC18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC18-to-partner and partner-to-ZDHHC18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC18→partner) and Y-score (partner→ZDHHC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GJD2 →	+0.004	+4.437	<.001	.004	3	1
LARGE_INTESTINE	SLC15A5 →	+0.016	+5.000	<.001	<.001	3	1
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
LARGE_INTESTINE	FAM205A →	+0.032	+3.614	<.001	.006	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

ZDHHC18 survival (RNA) · tumor vs normal (RNA) · all ZDHHC18 data types