Across TCGA patient cohorts, ZDHHC17 protein abundance is significantly associated with the RNA expression of many other genes, with 5,020 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZDHHC17-associated genes across cancer lineages are JHY, ANXA1, and SNX10. Each is linked with ZDHHC17 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZDHHC17-to-partner and partner-to-ZDHHC17 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC17→partner) and Y-score (partner→ZDHHC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	JHY →	+1.051	+0.477	<.001	.001	3	3
LSCC	ANXA1 →	-0.847	-0.178	.001	.001	3	3
HNSC	SNX10 →	+0.930	+0.343	<.001	<.001	3	3
HNSC	SPRR3 →	-1.801	-0.253	.003	<.001	3	2
GBM	BRD7 →	+0.373	+0.173	<.001	<.001	3	2
GBM	TRABD2B →	-0.274	-0.173	.008	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,020 associations by consensus.

Exploration

ZDHHC17 survival (RNA) · tumor vs normal (RNA) · all ZDHHC17 data types