ZDHHC17

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZDHHC17 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC17-associated genes across cancer lineages are 14-3-3_beta, FASN, and JNK2. Each is linked with ZDHHC17 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC17-to-partner and partner-to-ZDHHC17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC17→partner) and Y-score (partner→ZDHHC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.144-2.045<.001<.00132
UCECFASN →+0.439+2.058<.001<.00132
UCECJNK2 →+0.233+3.727<.001<.00132
UCECKu80 →+0.334+2.150<.001<.00132
UCECAkt_pT308 →+0.497+1.523.013.00832
UCECTuberin_pT1462 →+0.227+1.289.002.02332
Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration