Across TCGA cell cohorts, ZDHHC17 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZDHHC17-associated genes across cancer lineages are CCER1, CCL1, and MYF5. Each is linked with ZDHHC17 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC17-to-partner and partner-to-ZDHHC17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC17→partner) and Y-score (partner→ZDHHC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CCER1 →	+0.012	+4.754	<.001	.005	3	2
CNS	CCL1 →	+0.425	+4.472	<.001	.004	3	1
CNS	MYF5 →	+0.567	+4.321	<.001	.009	3	1
CNS	WFDC10A →	+0.063	+4.315	.007	.006	3	1
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	TECTB →	+0.063	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

ZDHHC17 survival (RNA) · tumor vs normal (RNA) · all ZDHHC17 data types