ZDHHC16

Across TCGA patient cohorts, ZDHHC16 protein abundance is significantly associated with the RNA expression of many other genes, with 1,458 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZDHHC16-associated genes across cancer lineages are MMP9, CSF2RB, and LILRB1. Each is linked with ZDHHC16 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZDHHC16-to-partner and partner-to-ZDHHC16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC16 versus MMP9 in GBM, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC16→partner) and Y-score (partner→ZDHHC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MMP9 →	-3.549	-1.210	<.001	<.001	3	3
UCEC	CSF2RB →	-0.772	-0.712	.004	.001	3	2
UCEC	LILRB1 →	-1.027	-1.089	.003	.001	3	2
UCEC	JAK3 →	-0.940	-0.900	.004	.006	3	2
LUAD	CCL8 →	-1.504	-0.543	<.001	.007	3	2
LUAD	CD274 →	-1.176	-0.695	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,458 associations by consensus.

ZDHHC16 vs MMP9 — GBM

Explore this scatter interactively →