ZDHHC16

Across TCGA cell cohorts, ZDHHC16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,153 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZDHHC16-associated GO terms across cancer lineages are Spindle elongation, Ornithine metabolic process, and Regulation of chromosome separation. Each is linked with ZDHHC16 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZDHHC16-to-partner and partner-to-ZDHHC16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by ZDHHC16-low versus ZDHHC16-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC16→partner) and Y-score (partner→ZDHHC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Spindle elongation →	+0.212	+0.609	.002	.002	3	13
PANCREAS	Ornithine metabolic process →	+0.122	+0.627	<.001	<.001	3	11
PANCREAS	Regulation of chromosome separation →	+0.118	+0.643	<.001	.001	3	10
BONE	Spindle midzone assembly →	+0.293	+0.585	.004	.004	2	11
BLOOD_Leukemia	Regulation of mitotic cytokinetic process →	+0.117	+0.494	<.001	<.001	3	10
BLOOD_Leukemia	Positive regulation of mitotic cytokinetic process →	+0.117	+0.494	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,153 associations by consensus.

Spindle elongation by ZDHHC16 expression — PANCREAS

Explore this box plot interactively →