ZDHHC14

Across TCGA cell cohorts, ZDHHC14 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,639 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZDHHC14-associated GO terms across cancer lineages are Regulation of modification of postsynaptic structure, Regulation of calcium ion export across plasma membrane, and Regulation of translational initiation. Each is linked with ZDHHC14 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZDHHC14-to-partner and partner-to-ZDHHC14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of modification of postsynaptic structure grouped by ZDHHC14-low versus ZDHHC14-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC14→partner) and Y-score (partner→ZDHHC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of modification of postsynaptic structure →	+0.129	+1.043	<.001	<.001	3	8
LARGE_INTESTINE	Regulation of calcium ion export across plasma membrane →	+0.066	+0.995	<.001	<.001	3	8
BLOOD_Lymphoma	Regulation of translational initiation →	+0.056	+1.266	<.001	.002	3	8
LARGE_INTESTINE	2-oxoglutarate decarboxylation to succinyl-CoA →	+0.099	+0.765	.004	.003	2	9
LARGE_INTESTINE	Regulation of phenotypic switching →	+0.097	+0.790	<.001	<.001	3	8
SKIN	Positive regulation of neuron migration →	+0.074	+0.805	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,639 associations by consensus.

Regulation of modification of postsynaptic structure by ZDHHC14 expression — LARGE_INTESTINE

Explore this box plot interactively →