ZDHHC13

Across TCGA patient cohorts, ZDHHC13 mutation is significantly associated with the RNA expression of many other genes, with 2,216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC13-associated genes across cancer lineages are RNA5SP411, RNU6-919P, and RN7SL134P. Each is linked with ZDHHC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC13-to-partner and partner-to-ZDHHC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by ZDHHC13-low versus ZDHHC13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC13→partner) and Y-score (partner→ZDHHC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+0.709	+1.628	.003	.005	3	2
BRCA	RNU6-919P →	+0.358	+5.610	<.001	.004	3	2
UCEC	RN7SL134P →	+0.092	+2.084	.002	.002	3	2
UCEC	GYG2P1 →	+0.027	+1.648	<.001	.006	3	2
UCEC	IGHD1-26 →	+0.440	+2.347	<.001	.003	3	2
UCEC	LINC00363 →	+0.093	+2.504	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,216 associations by consensus.

RNA5SP411 by ZDHHC13 expression — UCEC

Explore this box plot interactively →