ZDHHC13

Across TCGA cell cohorts, ZDHHC13 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZDHHC13-associated genes across cancer lineages are CABCOCO1, OR5B17, and IQCF5. Each is linked with ZDHHC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC13-to-partner and partner-to-ZDHHC13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CABCOCO1 grouped by ZDHHC13-low versus ZDHHC13-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC13→partner) and Y-score (partner→ZDHHC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CABCOCO1 →	+0.153	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	OR5B17 →	+0.044	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	IQCF5 →	+0.082	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	SCYGR1 →	+0.579	+4.867	<.001	.009	3	1
LUNG_NSCLC_LUAD	GTSF1L →	+0.055	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	HES3 →	+0.098	+4.212	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

CABCOCO1 by ZDHHC13 expression — BLOOD_Myeloma

Explore this box plot interactively →