ZDHHC12

Across TCGA patient cohorts, ZDHHC12 protein abundance is significantly associated with the RNA expression of many other genes, with 428 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZDHHC12-associated genes across cancer lineages are KATNAL1, PDGFRL, and CXCL12. Each is linked with ZDHHC12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC12-to-partner and partner-to-ZDHHC12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC12 versus KATNAL1 in GBM, with a Pearson correlation of -0.96.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC12→partner) and Y-score (partner→ZDHHC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KATNAL1 →	-0.913	-0.540	.008	.009	3	1
GBM	PDGFRL →	+1.790	+0.503	.008	.006	3	1
GBM	CXCL12 →	+1.797	+0.424	.003	.007	3	1
GBM	MAP3K8 →	+1.670	+0.540	.002	.009	3	1
GBM	P2RX1 →	+0.976	+0.646	.006	.003	3	1
GBM	POMC →	+0.854	+0.424	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

ZDHHC12 vs KATNAL1 — GBM

Explore this scatter interactively →