Across TCGA cell cohorts, ZDHHC11 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZDHHC11-associated genes across cancer lineages are SCYGR10, SLC32A1, and APOL5. Each is linked with ZDHHC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC11-to-partner and partner-to-ZDHHC11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC11→partner) and Y-score (partner→ZDHHC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SCYGR10 →	+0.212	+3.906	<.001	.009	3	1
BLOOD_Leukemia	SLC32A1 →	+0.499	+3.901	.004	.006	3	1
BLOOD_Leukemia	APOL5 →	+0.012	+4.060	.002	.003	3	1
BLOOD_Leukemia	NPFFR1 →	+0.015	+4.037	<.001	.004	3	1
BLOOD_Leukemia	KRTAP4-4 →	+0.016	+4.984	<.001	.002	3	1
BLOOD_Leukemia	PRR30 →	+0.015	+4.269	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

ZDHHC11 survival (RNA) · tumor vs normal (RNA) · all ZDHHC11 data types