ZDHHC1

Across TCGA patient cohorts, ZDHHC1 protein abundance is significantly associated with the RNA expression of many other genes, with 257 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZDHHC1-associated genes across cancer lineages are PVALB, AQP8, and GALNT8. Each is linked with ZDHHC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC1-to-partner and partner-to-ZDHHC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC1 versus PVALB in UCEC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC1→partner) and Y-score (partner→ZDHHC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PVALB →	+0.355	+0.496	.002	.004	3	1
UCEC	AQP8 →	+0.306	+0.496	.005	.004	3	1
UCEC	GALNT8 →	+0.207	+0.496	<.001	.004	3	1
UCEC	CHRND →	+0.617	+0.491	.007	.004	3	1
UCEC	FTCD →	+0.603	+0.491	<.001	.004	3	1
UCEC	HTR3A →	-0.230	-0.443	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 257 associations by consensus.

ZDHHC1 vs PVALB — UCEC

Explore this scatter interactively →