Across TCGA patient cohorts, ZDBF2 mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDBF2-associated genes across cancer lineages are Rab25, Rictor, and 4E-BP1. Each is linked with ZDBF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZDBF2-to-partner and partner-to-ZDBF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDBF2→partner) and Y-score (partner→ZDBF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Rab25 →	-0.354	-3.169	.010	.018	3	3
STAD	Rictor →	-0.804	-1.700	.036	.042	3	3
STAD	4E-BP1 →	+0.399	+3.169	<.001	.017	3	3
BRCA	Notch1 →	+0.277	+2.466	<.001	.012	3	3
BRCA	4E-BP1_pT70 →	+0.280	+3.000	.001	.037	3	3
UCEC	eIF4E →	+0.185	+1.657	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Exploration

ZDBF2 survival (RNA) · tumor vs normal (RNA) · all ZDBF2 data types