ZDBF2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZDBF2 mutation is significantly associated with the RNA expression of many other genes, with 365 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZDBF2-associated genes across cancer lineages are PRSS37, KRTAP10-1, and CT45A2. Each is linked with ZDBF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDBF2-to-partner and partner-to-ZDBF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDBF2→partner) and Y-score (partner→ZDBF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEPRSS37 →+0.031+3.058<.001.00432
SOFT_TISSUEKRTAP10-1 →+0.031+3.632<.001.00132
SOFT_TISSUECT45A2 →+1.050+2.832<.001.00532
BREASTTRIT1 →+0.505+3.510.007<.00132
LARGE_INTESTINECCDC134 →+0.539+2.131.008.00332
LARGE_INTESTINEHMGXB4 →+0.508+2.043.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 365 associations by consensus.

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